what are the side effects of fibator ez

Question (Posted on :  13 Jun 2009 )


what are the side effects of fibator ez

Doctor's Response (Posted on : 13 Jun 2009 )


it contains atorvastatin,feno fibrate and ezetemibe. atorvastatin decreases the production of cholesterol while ezetimibe reduces the absorption of cholesterol from the intestines..fenofibrate acts by reducing ldl levels and increasing hdl levels...all three help in reducing lipid levels in the body.. it is not advisable to take atorvastatin with fenofibrate as they interact with each other and increase risk of myopathy and rhabdomyolysis...in simple words muscle degeneration and pain....however recent studies have shown no fruitful information against this.hence usage should be under strict medical supervision where dosage can be changed as and when required. this drug can be tolerated upto 48 weeks.. side effects could include... myopathy with elevation of creatinine kinase (CK) and rhabdomyolysis are the most serious, although rare lt;1%. * Headache is the most common side effect, occurring in more than 10% of patients. Side effects that occur in 1-10% of patients taking atorvastatin include: * Weakness * Insomnia and dizziness. * Chest pain and peripheral edema. * Rash * Abdominal pain, constipation, diarrhea, dyspepsia, flatulence, nausea. * Urinary tract infection * Arthralgia, myalgia, back pain, arthritis * Sinusitis, pharyngitis, bronchitis, rhinitis * Infection, flu-like syndrome, allergic reaction. Elevation of alanine transaminase (ALT) and aspartate transaminase (AST) has been described in a few cases Other very rare side effects occurring in less than 1% of patients are: alopecia, anaphylaxis, angina, angioneurotic edema, arrhythmia, bullous rashes, cholestatic jaundice, deafness, dyspnea, erythema multiforme, esophagitis, facial paralysis, glaucoma, gout, hepatitis, hyperkinesia, impotence, migraine, myasthenia, myositis, nephritis, pancreatitis, paresthesia, peripheral neuropathy, petechiae, photosensitivity, postural hypotension, pruritus, rectal hemorrhage, rhabdomyolysis, somnolence, Stevens-Johnson syndrome, syncope, tendinous contracture, thrombocytopenia, tinnitus, torticollis, toxic epidermal necrolysis, urticaria, vaginal hemorrhage, and vomiting Side-effects also include gastro-intestinal disturbances; headache, fatigue; myalgia; rarely arthralgia, hypersensitivity reactions (including rash, angioedema, and anaphylaxis), hepatitis; very rarely pancreatitis, cholelithiasis, cholecystitis, thrombocytopenia...


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